- Advancedgout.Untreatedgoutmaycausedepositofuratecrystalstoformundertheskininnodulescalledtophi(TOE-fi).Insomepatients,thatcanleadtotheaccumulationofpainfulknotsofcrystallizeduricacidthatcanbethesizeofgolfballs(calledtophi)thatformaroundthejointsandte...
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